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Stem Cell Related Patent Number US4831117
| Title: | Monoclonal antibody specific for human B-cells | | Inventors: | Uckun, Fatih M.; Minneapolis, MN, USA | | Summary: | This invention introduces properties of the B-lineage restricted IgG monoclonal antibody, and therapeutic uses thereof. Described herein is a hybridoma which secretes a B-lineage restricted monoclonal antibody of isotype IgG, having all the identifying characteristics of the hybrid cell line ATCC HB 8903. Further disclosed is a process by which this hybridoma and associated monoclonal antibody may be utilized to form an immunotoxin for purging autologous grafts for bone marrow transplantation. Specific therapeutic applications are included for the treatment of lymphoblastic leukemia. | | Abstract: | | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US4831117 | | Application Number: | US1986000816141 | | Date Filed: | 03/01/1986 | | Date Published: | 16/05/1989 | | Assignee: | None |
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