Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US4987121

Title:Erythropoietic factor
Inventors:Baertschi, Alex J.; Charlottesville, VA, USA
Niskanen, Eero; Charlottesville, VA, USA
Summary:This invention introduces a method for the potentiation of erythropoietin (Epo) using an atrial natriuretic factor (ANF) which has been shown to increase the production of erythroid progenitor cells. Described herein is a process of administering an ANF alone or in combination with Epo such that the ANF potentiates the activity of Epo and causes production of the erythroid progenitors BFU-E and CFU-E. Claims of the invention include the generation of red blood cells at a higher level than if Epo alone is present in the blood stream. Therapeutic applications are included for the treatment of anemia.
Abstract:
US Patent Website:Click Here for Full Text of Patent
Title Number:US4987121
Application Number:US1988000199438
Date Filed:27/05/1988
Date Published:22/01/1991
Assignee:Center for Innovative Technology, Herndon, VA, USA University of Virginia, Charlottesville, VA, USA


 
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