Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US5197985

Title:Method for enhancing the implantation and differentiation of marrow-derived mesenchymal cells
Inventors:Caplan, Arnold I.; Cleveland Heights, OH, USA
Haynesworth, Stephen E.; Cleveland Heights, OH, USA
Summary:Described herein are processes for enhancing implantation and differentiation of marrow-derived mesenchymal cells. The invention relates to methods and materials for enhancing the implantation and differentiation of mesenchymal stem cells via their isolation, purification and cultural expansion, after which they are then applied to a substrate surface and a porous carrier which is implanted into an appropriate environment with suitable factors to allow for the differentiation of the mesenchymal stem cells into bone cells. Therapeutic applications are directed toward the treatment of skeletal and other connective tissue injuries and disorders.
Abstract:The present invention is directed to a method and device for enhancing the implantation and differentiation of marrow-derived mesenchymal cells (i.e. mesenchymal stem cells). The method and device of the invention are an effective means for treating skeletal and other connective tissue disorders.
US Patent Website:Click Here for Full Text of Patent
Title Number:US5197985
Application Number:US1990000614915
Date Filed:16/11/1990
Date Published:30/03/1993
Assignee:None


 
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