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Stem Cell Related Patent Number US5384331
| Title: | Ketamine analogues for treatment of thrombocytopenia | | Inventors: | Kogan, Timothy P.; Half Moon Bay, CA, USA
Somers, Todd C.; Montara, CA, USA | | Summary: | Described herein are methods of treating thrombocytopenia by the administration of cyclohexene derivatives. The invention relates to 5,6-Dehydronorketamine and derivatives which retain the ?a,?-unsaturated carbonyl and which are shown to influence the replication, differentiation and maturation of blood cells such as platelet progenitor cells in a manner similar to that of Michael or Michael-type acceptors and adducts. Therapeutic applications of such compounds are directed toward the treatment of thrombocytopenia. | | Abstract: | | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US5384331 | | Application Number: | US1993000069245 | | Date Filed: | 28/05/1993 | | Date Published: | 24/01/1995 | | Assignee: | Genentech, Inc., South San Francisco, CA, USA |
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