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Stem Cell Related Patent Number US5409813
| Title: | Method for mammalian cell separation from a mixture of cell populations | | Inventors: | Schwartz, Richard M.; San Mateo, CA, USA | | Summary: | Described herein is a process of selectively separating at least one mammalian target cell population from a suspension of a mixture of cell populations via the use of a magnetically stabilized and fluidized bed which contains a substance with an affinity for the target cells. The invention relates to a method for both the positive and negative selection of mammalian cell populations from a mixture according to a process by which a column containing a bed of magnetizable particles with an affinity for the target cell population is fluidized with a radially and axially uniform magnetic field through which the suspension is passed which results in the binding of the particles to the target cell population which may then be collected. A variety of therapeutic and experimental applications are included. | | Abstract: | The invention provides a method for both the positive and negative selection of at least one mammalian cell population from a mixture of cell populations utilizing a magnetically stabilized fluidized bed. One desirable application of this method is the separation and purification of mammalian hematopoietic cells. Target cell populations include human stem cells. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US5409813 | | Application Number: | US1993000130094 | | Date Filed: | 30/09/1993 | | Date Published: | 25/04/1995 | | Assignee: | SyStemix, Inc., Palo Alto, CA, USA |
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