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Stem Cell Related Patent Number US5595721
| Title: | Radioimmunotherapy of lymphoma using anti-CD20 | | Inventors: | Kaminski, Mark S.; Ann Arbor, MI, USA
Butchko, Gregory M.; Miami Lakes, FL, USA
Glenn, Stephan D.; Davie, FL, USA
Wahl, Richard L.; Ann Arbor, MI, USA | | Summary: | Described herein is a method of treating lymphoma by radioimmunotherapy. The invention relates to the administration of a B cell-specific antibody to a patient in conjunction with a regimen by which the patient receives both unlabeled antibodies and antibodies labeled with a radioisotope. Claims of the invention include improved tumor responses that are obtained within a radiometric dose range that does not require hematopoietic stem cell replacement as an adjunct therapy. | | Abstract: | Methods for the treatment of lymphoma by adminstration of a B cell-specific antibody are described. The invention encompasses providing to a patient both unlabeled antibodies and antibodies labeled with a radioisotope. A principal advantage of the method is that tumor responses can be obtained in a radiometric dose range that does not require hematopoietic stem cell replacement as an adjunct therapy. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US5595721 | | Application Number: | US1993000121582 | | Date Filed: | 16/01/1993 | | Date Published: | 21/01/1997 | | Assignee: | Coulter Pharmaceutical, Inc., Palo Alto, CA, USA |
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