Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US5595721

Title:Radioimmunotherapy of lymphoma using anti-CD20
Inventors:Kaminski, Mark S.; Ann Arbor, MI, USA
Butchko, Gregory M.; Miami Lakes, FL, USA
Glenn, Stephan D.; Davie, FL, USA
Wahl, Richard L.; Ann Arbor, MI, USA
Summary:Described herein is a method of treating lymphoma by radioimmunotherapy. The invention relates to the administration of a B cell-specific antibody to a patient in conjunction with a regimen by which the patient receives both unlabeled antibodies and antibodies labeled with a radioisotope. Claims of the invention include improved tumor responses that are obtained within a radiometric dose range that does not require hematopoietic stem cell replacement as an adjunct therapy.
Abstract:Methods for the treatment of lymphoma by adminstration of a B cell-specific antibody are described. The invention encompasses providing to a patient both unlabeled antibodies and antibodies labeled with a radioisotope. A principal advantage of the method is that tumor responses can be obtained in a radiometric dose range that does not require hematopoietic stem cell replacement as an adjunct therapy.
US Patent Website:Click Here for Full Text of Patent
Title Number:US5595721
Application Number:US1993000121582
Date Filed:16/01/1993
Date Published:21/01/1997
Assignee:Coulter Pharmaceutical, Inc., Palo Alto, CA, USA


 
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