Methods comprising apoptosis inhibitors for the generation of transgenic pigs

Stem Cell Clinic
Patient Application
FAQ
Contact
Locations
News
Videos
Research
Patents
3D Culture/Scaffold
Administration
Differentiation
Expansion
Extraction/Preservation
Mobilization
Type
USE
 


Stem Cell Related Patent Number US5614397

Title:Method and compositions for modulating lifespan of hematolymphoid cells
Inventors:Weissman, Irving; Redwood City, CA, USA
Summary:Described herein is a system for increasing the life-span of mammalian hematolymphoid cells in vitro. The invention relates to methods and materials of transforming the stem cells with a construct containing a cell-specific transcription initiator and gene-encoding protein that modifies the life-span of the progeny cells of mammalian hematopoietic stem cells such as the myeloid series of cells. Further disclosed are transgenic nonhuman mammals which produce the transgenic myeloid cells having an altered life-span. Applications are included for the screening of drugs.
Abstract:Methods and compositions for modifying the lifespan of progeny cells of mammalian hematopoietic stem cells, particularly myeloid series cells, are provided. Transgenic nonhuman mammals also are provided which produce transgenic myeloid cells having an altered lifespan.
US Patent Website:Click Here for Full Text of Patent
Title Number:US5614397
Application Number:US1994000200016
Date Filed:22/02/1994
Date Published:25/03/1997
Assignee:Board of Trustees of the Leland Stanford Junior University, Stanford, CA, USA


 
Copyright © 2007 The Institute for Cellular Medicine  6/22/2021