Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US5681694

Title:Murd protein method and kit for identification of inhibitors
Inventors:Hoskins, Jo Ann; Indianapolis, IN, USA
Peery, Robert Brown; Brownsburg, IN, USA
Skatrud, Paul Luther; Indianapolis, IN, USA
Wu, Chyun-Yeh Earnest; Indianapolis, IN, USA
Summary:Described herein is the Streptococcus pneumoniae MurD protein, and methods of its use in the screening of antibacterial drugs. The invention relates to isolated nucleic acid compounds encoding the MurD stem peptide biosynthetic gene of Streptococcus pneumoniae, as well as associated vectors by which heterologous host cells are transformed for expressing the MurD enzyme product. Further provided is a kit for identifying compounds that inhibit stem peptide biosynthesis. This invention represents a variation of other applications filed by the same assignee.
Abstract:The invention provides isolated nucleic acid compounds encoding the murD stem peptide biosynthetic gene of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the MurD enzyme product and a method for identifying compounds that inhibit stem peptide biosynthesis.
US Patent Website:Click Here for Full Text of Patent
Title Number:US5681694
Application Number:US1996000665435
Date Filed:18/06/1996
Date Published:28/10/1997
Assignee:Eli Lilly and Company, Indianapolis, IN, USA


 
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