Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US5712108

Title:Peptidoglycan biosynthetic mure protein from streptocuccus pneumoniae
Inventors:Peery, Robert Brown; Brownsburg, IN, USA
Skatrud, Paul Luther; Indianapolis, IN, USA
Summary:Described herein is a Streptococcus pneumoniae MurE protein, methods and uses thereof. The invention relates to isolated nucleic acid compounds encoding the murE stem peptide biosynthetic gene of Streptococcus pneumoniae, and vectors by which heterologous host cells are transformed for expressing the MurE enzyme product. Further disclosed is a method for identifying compounds that inhibit stem peptide biosynthesis and which may be used therapeutically for the screening of anti-bacterial agents. This invention represents a variation of other applications filed by the same assignee
Abstract:The invention provides isolated nucleic acid compounds encoding the murE stem peptide biosynthetic gene of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the murE enzyme product and a method for identifying compounds that inhibit stem peptide biosynthesis.
US Patent Website:Click Here for Full Text of Patent
Title Number:US5712108
Application Number:US1996000655114
Date Filed:29/05/1996
Date Published:27/01/1998
Assignee:Eli Lilly and Company, Indianapolis, IN, USA


 
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