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Stem Cell Related Patent Number US5759793
| Title: | Method for mammalian cell separation from a mixture of cell populations | | Inventors: | Schwartz, Richard M.; San Mateo, CA, USA
Elkalay, Mohammed A.; Cupertino, CA, USA | | Summary: | This invention introduces a method for both the positive and negative selection of a target mammalian cell population from a suspension mixture of multiple cell populations via the use of a magnetically stabilized and fluidized bed. The bed is described herein as containing a plurality of magnetizable nanoparticles with an affinity for target cells resulting in the separation of the target cells from the bed. Claims of the invention include the separation and purification of hematopoietic cells by this process, and target cell populations which may include any lineage of human stem cells. | | Abstract: | The invention provides a method for both the positive and negative selection of at least one mammalian cell population from a mixture of cell populations utilizing a magnetically stabilized fluidized bed. One desirable application of this method is the separation and purification of hematopoietic cells. Target cell populations include human stem cells. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US5759793 | | Application Number: | US1996000615201 | | Date Filed: | 06/08/1996 | | Date Published: | 02/06/1998 | | Assignee: | SyStemix, Inc., Palo Alto, CA, USA |
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