Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US5763197

Title:Human hematopoietic stem cell
Inventors:Tsukamoto, Ann; Palo Alto, CA, USA
Baum, Charles M.; Mountain View, CA, USA
Aihara, Yukoh; Yokohama, Japan
Weissman, Irving; Palo Alto, CA, USA
Summary:This invention describes an assay for identifying growth factors according to a process by which a sample of Thy-1+ human hematopoietic stem cells is evaluated for its self-regeneration capacity. Described herein are human hematopoietic stem cells and methods by which they are separated from dedicated cells and maintained by regeneration in an appropriate growth medium, after which they are assayed for their capacity to produce members of each of the hematopoietic lineages. Therapeutic and experimental applications to the treatment of hematopoietic diseases are included. This invention represents a continuation of other applications filed by the same assignee and inventors.
Abstract:Human hematopoietic stem cells are provided by separation of the stem cells from dedicated cells. The stem cells may than be maintained by regeneration in an appropriate growth medium. Means are provided for assaying for the stem cells as to their capability for producing members of each of the hematopoietic lineages.
US Patent Website:Click Here for Full Text of Patent
Title Number:US5763197
Application Number:US1991000720883
Date Filed:25/06/1991
Date Published:09/06/1998
Assignee:SyStemix, Inc., Palo Alto, CA, USA


 
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