Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US5827742

Title:Method of selecting pluripotent hematopioetic progenitor cells
Inventors:Scadden, David T.; Weston, MA, USA
Summary:Described herein is a selection technique for a population of mammalian cells which contains quiescent pluripotent hematopoietic progenitor cells and which is substantially free of mature, myeloid and lymphoid cells. Further disclosed are properties of the quiescent pluripotent progenitor cells and methods of their use. Therapeutic applications are included for the re-population of human bone marrow such as in the treatment of leukemia.
Abstract:Methods of selecting a population of human cells containing quiescent pluripotent hematopoietic progenitor cells substantially free of mature, human myeloid and lymphoid cells, the quiescent pluripotent progenitor cells obtained by these methods, and methods of using the pluripotent progenitor cells are described.
US Patent Website:Click Here for Full Text of Patent
Title Number:US5827742
Application Number:US1994000299902
Date Filed:01/09/1994
Date Published:27/10/1998
Assignee:Beth Israel Deaconess Medical Center, Boston, MA, USA


 
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