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Stem Cell Related Patent Number US5843438
| Title: | Peripheralization of hematopoietic stem cells | | Inventors: | Papayannopoulou, Thalia; Seattle, WA, USA | | Summary: | This invention describes a method of peripheralizing CD34+ hematopoietic stem cells in vivo via the administering of an anti-VLA-4 antibody or an anti-VCAM-1 antibody which blocks the binding of VLA-4 antigen on the surface of the CD34+ cells to VCAM or fibronectin. Also disclosed are methods of in vivo peripheralization of the CD34+ cells by administering anti-VLA-4 antibodies or anti-VCAM-1 antibodies. | | Abstract: | The invention relates to in vivo peripheralization of CD34.sup.+ cells by administering anti-VLA-4 antibodies or anti-VCAM-1 antibodies. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US5843438 | | Application Number: | US1995000436339 | | Date Filed: | 13/07/1995 | | Date Published: | 01/12/1998 | | Assignee: | Board of Regents of the University of Washington, Seattle, WA, USA |
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