Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US5851832

Title:In vitro growth and proliferation of multipotent neural stem cells and their progeny
Inventors:Weiss, Samuel; Alberta, Canada
Reynolds, Brent; Alberta, Canada
Hammang, Joseph P.; Barrington, RI, USA
Baetge, E. Edward; Barrington, RI, USA
Summary:Described herein are methods for the in vitro culturing of neural stem cells and their progeny. The invention relates to processes by which such cells are isolated from a mammal, exposed to a culture medium containing a growth factor, induced to proliferate and further induced to differentiate into glia and neurons including astrocytes. Therapeutic applications in neurophysiological pathologies are included for differentiated neural cells produced according to this manner.
Abstract:A method for the in vitro proliferation and differentiation of neural stem cells and stem cell progeny comprising the steps of (a) isolating the cells from a mammal, (b) exposing the cells to a culture medium containing a growth factor, (c) inducing the cells to proliferate, and (d) inducing the cells to differentiate is provided.
US Patent Website:Click Here for Full Text of Patent
Title Number:US5851832
Application Number:US1995000486648
Date Filed:07/06/1995
Date Published:22/12/1998
Assignee:NeuroSpheres, Ltd. Canada


 
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