Methods comprising apoptosis inhibitors for the generation of transgenic pigs

Stem Cell Clinic
Patient Application
FAQ
Contact
Locations
News
Videos
Research
Patents
3D Culture/Scaffold
Administration
Differentiation
Expansion
Extraction/Preservation
Mobilization
Type
USE
 


Stem Cell Related Patent Number US5854071

Title:OP-3- induced morphongenesis
Inventors:Oppermann, Hermann; Medway, MA, USA
Ozkaynak, Engin; Milford, MA, USA
Kuberasampath, Thangavel; Medway, MA, USA
Rueger, David C.; Hopkinton, MA, USA
Pang, Roy H. L.; Etna, NH, USA
Cohen, Charles M.; Medway, MA, USA
Summary:This invention introduces the morphogenically active protein MOP-3, methods and uses thereof. Described herein are nucleic acid and amino acid sequences for MOP-3, methods for its production and expression in a biologically active form, and methods for its utilization in the induction of tissue morphogenesis in a mammal. Claims of the invention include the induction of endochondral bone formation in an in vivo assay, an increase in the progenitor cell population, and the ability of MOP-3 to stimulate progenitor cells to differentiate and maintain their differentiated phenotype both in vivo and in vitro. Therapeutic applications are included for inducing tissue-specific growth in vivo for the replacement of diseased or damaged tissue.
Abstract:
US Patent Website:Click Here for Full Text of Patent
Title Number:US5854071
Application Number:US1997000901200
Date Filed:28/07/1997
Date Published:29/12/1998
Assignee:Creative BioMolecules, Inc., Boston, MA, USA


 
Copyright © 2007 The Institute for Cellular Medicine  6/13/2021