Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US5874399

Title:Progenitor B cell stimulating factor
Inventors:Samal, Babru Bahan; Moorpark, CA, USA
Summary:This invention introduces a purified progenitor B cell stimulating factor which promotes the formation of pre-B cells. Further disclosed are specific DNA amino acid sequences of the factor, which is described as a polypeptide that stimulates the production of pre-B cells in the presence of a stem cell factor and interleukin-7. Methods of purification and production of the factor are provided, as are therapeutic applications for the treatment of hematopoietic disorders and bone marrow transplantation.
Abstract:
US Patent Website:Click Here for Full Text of Patent
Title Number:US5874399
Application Number:US1995000448735
Date Filed:24/05/1995
Date Published:23/02/1999
Assignee:Amgen Inc., Thousand Oaks, CA, USA


 
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