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Stem Cell Related Patent Number US5939391
| Title: | Hemoglobin alpha chain peptide fragments useful for inhibiting stem cell proliferation | | Inventors: | Tsyrlova, Irena; Gaithersburg, MD, USA
Wolpe, Stephen D.; Rockville, MD, USA | | Summary: | Described herein are inhibitors of stem cell proliferation comprised of hemoglobin chains, methods and uses thereof. The invention relates to the isolation and use of stem cell inhibiting factors for the regulation of the abnormal stem cell cycle and for the acceleration of post-chemotherapy peripheral blood cell recovery. Further disclosed are properties of the inhibitors of stem cell proliferation. Therapeutic applications are included in the treatment of cancer, in the maintenance of mammalian hematopoietic stem cells ex vivo, and for the protection of stem cells from antiviral agents. | | Abstract: | Disclosed and claimed are methods for the isolation and use of stem cell inhibiting factors for regulating the abnormal stem cell cycle and for accelerating the post-chemotherapy peripheral blood cell recovery. Also disclosed and claimed are the inhibitors of stem cell proliferation. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US5939391 | | Application Number: | US1995000535882 | | Date Filed: | 28/09/1995 | | Date Published: | 17/08/1999 | | Assignee: | Pro-Neuron, Inc., Rockville, MD, USA |
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