Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US5985659

Title:Embryonic stem cell lines obtained from C3H/HeN and DBA/1J mouse strains
Inventors:KUSA
kabe, Moriaki; Ibaragi, Japan
Kamon, Toshio; Tokyo, Japan
Summary:Described herein are embryonic stem cells derived from inbred mouse strains. The invention relates to methods of producing knock-out mice from inbred mouse strains selected from the group consisting of C3H/HeN, C57BL/6N, DBA/1J, and BALB/c, including the C-2 cell strain with the accession number FERM BP-5933, and the C-6 cell strain with the accession number FERM BP-5934. Experimental applications of such embryonic stem cell lines are included for the analysis of cell genealogical trees in genetic research.
Abstract:Embryonic stem cells derived from an inbred mouse strain selected from the group consisting of C3H/HeN, C57BL/6N, DBA/1J, and BALB/c strains, for example, C-2 cell having the accession number FERM BP-5933 and C-6 cell having the accession number FERM BP-5934 are disclosed. The embryonic stem cells of the present invention are derived from genetically complete inbred strains, and therefore, they are extremely useful for close genetic research.
US Patent Website:Click Here for Full Text of Patent
Title Number:US5985659
Application Number:US1997000859290
Date Filed:20/05/1997
Date Published:16/11/1999
Assignee:The Institute of Physical and Chemical Research, Saitama, Japan


 
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