Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US6020469

Title:Stem cell factor formulations and methods
Inventors:Hershenson, SUSA
n I.; Newbury Park, CA, USA
Summary:This invention introduces novel lyophilised stem cell factor (SCF) formulations containing histidine and glutamic acid, methods and uses thereof. The invention relates to a process of preparing a lyophilized SCF by mixing the SCF with histidine and/or glutamic acid and lyophilizing the formulation. An alternate embodiment of the invention includes a bulking agent or an osmolarity regulating agent which may be added prior to lyophilization. Claims of the invention include increased stability and extended shelf-life.
Abstract:Disclosed is a method of preparing a lyophilized stem cell factor (SCF). The method comprises mixing the SCF with histidine and/or glutamic acid and lyophilizing the formulation. Optionally, a bulking agent or an osmolarity regulating agent is included in the formulation prior to lyophilization.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6020469
Application Number:US1999000292222
Date Filed:15/04/1999
Date Published:01/02/2000
Assignee:Amgen Inc., Thousand Oaks, CA, USA


 
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