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Stem Cell Related Patent Number US6020469
| Title: | Stem cell factor formulations and methods | | Inventors: | Hershenson, SUSA
n I.; Newbury Park, CA, USA | | Summary: | This invention introduces novel lyophilised stem cell factor (SCF) formulations containing histidine and glutamic acid, methods and uses thereof. The invention relates to a process of preparing a lyophilized SCF by mixing the SCF with histidine and/or glutamic acid and lyophilizing the formulation. An alternate embodiment of the invention includes a bulking agent or an osmolarity regulating agent which may be added prior to lyophilization. Claims of the invention include increased stability and extended shelf-life. | | Abstract: | Disclosed is a method of preparing a lyophilized stem cell factor (SCF). The method comprises mixing the SCF with histidine and/or glutamic acid and lyophilizing the formulation. Optionally, a bulking agent or an osmolarity regulating agent is included in the formulation prior to lyophilization. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US6020469 | | Application Number: | US1999000292222 | | Date Filed: | 15/04/1999 | | Date Published: | 01/02/2000 | | Assignee: | Amgen Inc., Thousand Oaks, CA, USA |
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