Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US6022848

Title:Inhibitor of stem cell proliferation and uses thereof
Inventors:Kozlov, Vladimir; Novosibirisk, Russian Federation
Tsyrlova, Irena; Gaithersburg, MD, USA
Summary:Described herein are inhibitors of stem cell proliferation, methods and uses thereof. The invention relates to a process of inhibiting stem cell proliferation via contacting hematopoietic cells with a stem cell proliferation inhibiting amount of a composition containing various hemoglobin chains. Specific amino acid sequences are disclosed, as are associated properties and procedures. Therapeutic applications are included for use in the protection of stem cells from antiviral agents, in the treatment of cancer, and in the maintenance of mammalian hematopoietic stem cells ex vivo.
Abstract:Disclosed and claimed are methods for the isolation and use of stem cell inhibiting factors for regulating the abnormal stem cell cycle and for accelerating the post-chemotherapy peripheral blood cell recovery. Also disclosed and claimed are the inhibitors of stem cell proliferation.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6022848
Application Number:US1994000316424
Date Filed:30/09/1994
Date Published:08/02/2002
Assignee:Pro-Neuron, Inc., Rockville, MD, USA


 
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