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Stem Cell Related Patent Number US6068836
| Title: | Cell compositions for use in transplantation | | Inventors: | Quesenberry, Peter J.; Shrewsbury, MA, USA | | Summary: | Described herein are compositions of stem cell populations, methods and uses thereof. The invention relates to an ex vivo process by which pluripotent cells are expanded and optionally transfected to induce quiescence. Claims of the invention include improved long-term engraftment. Therapeutic applications in transplantation and gene therapy are provided. | | Abstract: | Methods for the preparation of bone marrow stem cell compositions for use in transplantation therapy and ex vivo gene therapy of a mammal. The methods involve the use of quiescent stem cells for transplantation therapy and quiescent transfected stem cells for ex vivo gene therapy. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US6068836 | | Application Number: | US1997000849276 | | Date Filed: | 25/08/1997 | | Date Published: | 30/05/2000 | | Assignee: | University of Massachusetts, Boston, MA, USA |
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