Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US6071889

Title:In vivo genetic modification of growth factor-responsive neural precursor cells
Inventors:Weiss, Samuel; Alberta, Canada
Reynolds, Brent; Alberta, Canada
Hammang, Joseph P.; Barrington, RI
Baetge, E. Edward; Barrington, RI
Summary:This invention describes methods for administering genetic material to dividing neural precursor cell populations in vivo. The genetic material may comprise useful genes for neurotransmitters, growth factors, and growth factor receptors, and the genetic material is administered to the brain with one or more growth factors. The growth factors induce proliferation of neural precursor cells, thereby facilitating the incorporation of the genetic material into the cell progeny.
Abstract:Methods for administering genetic material to dividing neural precursor cell populations in vivo are provided. The genetic material may comprise useful genes for neurotransmitters, growth factors, growth factor receptors, and the like. The genetic material is administered to the brain with one or more growth factors. The growth factors induce proliferation of neural precursor cells, thereby facilitating the incorporation of the genetic material into the cell progeny.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6071889
Application Number:US1995000479795
Date Filed:07/06/1995
Date Published:06/06/2000
Assignee:NeuroSpheres Holdings Ltd., Calgary, Canada


 
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