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Stem Cell Related Patent Number US6117675
| Title: | Retinal stem cells | | Inventors: | van der Kooy, Derek; Toronto, Canada
McInnes, Roderick; Ontario, Canada
Chiasson, Bernard; York, Canada
Tropepe, Vincenzo; Toronto, Canada | | Summary: | Described herein are retinal stem cells isolated and purified from mammalian retinae, methods and uses thereof. The invention relates to the means by which retinal stem cells are induced in vivo or in vitro to produce retinal cells. Further disclosed are pharmaceutical compositions containing the retinal stem cells or retinal cells, and methods by which such compositions may be used to restore vision that has been lost due to disease or injury. Additional therapeutic applications include the use of such retinal stem cells and retinal cell culture systems for toxicological assays, for isolating genes involved in retinal differentiation and for the development of tumor cell lines. | | Abstract: | The invention relates to stem cells isolated from the retina of mammals and retinal cells differentiated from these stem cells. The invention also relates to a method of isolating retinal stem cells and inducing retinal stem cells to produce retinal cells. Retinal stem cells may also be induced in vivo to produce retinal cells. The invention also includes pharmaceuticals made with retinal stem cells or retinal cells which may be used to restore vision lost due to diseases, disorders or abnormal physical states of the retina. The invention includes retinal stem cell and retinal cell culture systems for toxicological assays, for isolating genes involved in retinal differentiation or for developing tumor cell lines. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US6117675 | | Application Number: | US1997000937967 | | Date Filed: | 25/09/1997 | | Date Published: | 12/09/2000 | | Assignee: | HSC Research and Development Limited Partnership, Toronto, Canada |
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