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Stem Cell Related Patent Number US6153583
| Title: | OP-3 induced morphogenesis | | Inventors: | Oppermann, Hermann; Medway, MA, USA | | Summary: | Described herein are novel compositions containing a morphogenically active fragment of OP-3. The invention relates to nucleic acid and amino acid sequences for a novel morphogenic protein and the methods for producing and expressing the protein in a biologically active form. Further disclosed are methods for utilizing the protein to induce tissue morphogenesis in a mammal, including methods for increasing a progenitor cell population in a mammal and for stimulating the progenitor cells to differentiate and maintain their differentiated phenotype in vivo or in vitro. Therapeutic applications for inducing the formation of replacement tissue at a tissue locus in a mammal are included. | | Abstract: | | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US6153583 | | Application Number: | US1998000219391 | | Date Filed: | 23/12/1998 | | Date Published: | 28/11/2000 | | Assignee: | Stryker Corporation, Hopkinton, MA, USA |
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