Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US6153583

Title:OP-3 induced morphogenesis
Inventors:Oppermann, Hermann; Medway, MA, USA
Summary:Described herein are novel compositions containing a morphogenically active fragment of OP-3. The invention relates to nucleic acid and amino acid sequences for a novel morphogenic protein and the methods for producing and expressing the protein in a biologically active form. Further disclosed are methods for utilizing the protein to induce tissue morphogenesis in a mammal, including methods for increasing a progenitor cell population in a mammal and for stimulating the progenitor cells to differentiate and maintain their differentiated phenotype in vivo or in vitro. Therapeutic applications for inducing the formation of replacement tissue at a tissue locus in a mammal are included.
Abstract:
US Patent Website:Click Here for Full Text of Patent
Title Number:US6153583
Application Number:US1998000219391
Date Filed:23/12/1998
Date Published:28/11/2000
Assignee:Stryker Corporation, Hopkinton, MA, USA


 
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