Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US6171834

Title:Muri protein from Streptococcus pneumoniae
Inventors:Hoskins, Jo Ann; Indianapolis, IN, USA
Summary:This invention introduces a streptococcus pneumoniae muri protein, methods and uses thereof. Described herein are isolated nucleic acid compounds encoding the stem peptide biosynthetic gene muri of streptococcus pneumoniae. Further disclosed are vectors and transformed heterologous host cells for expressing the muri enzyme product, as well as methods for the identification of compounds inhibiting stem peptide biosynthesis. Therapeutic applications in antibacterial drug screening are provided.
Abstract:The invention provides isolated nucleic acid compounds encoding the stem peptide biosynthetic gene murI of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the MurI enzyme product and a method for identifying compounds that inhibit stem peptide biosynthesis.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6171834
Application Number:US1999000303272
Date Filed:30/04/1999
Date Published:09/01/2001
Assignee:Eli Lilly and Company, Indianapolis, IN, USA


 
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