Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US6177019

Title:Method and apparatus for removing tumor cells from tumor cell-contaminated stem cell products
Inventors:Castino, Franco; Sudbury, MA, USA
Wickramasinghe, Sumith R.; Marlborough, MA, USA
Summary:This invention describes a system of removing tumor cells from contaminated stem cell products via an in-line filtration process incorporating a tumor cell reduction filter preferably composed of one or more tumor cell reduction filter pads. Claims of the invention include a ten-fold reduction in tumor cells while allowing for at least a 30% recovery of stem cells in a filtered stem cell product.
Abstract:A method for removing tumor cells from tumor cell-contaminated stem cell products is disclosed. One embodiment of the method relies on an in-line filtration device that includes a tumor cell reduction filter means, preferably comprised of one or more tumor cell reduction filter pads. The tumor cell reduction filter means provides at least a ten-fold reduction in tumor cells while allowing for at least a 30% recovery of stem cells in a filtered stem cell product.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6177019
Application Number:US1999000242857
Date Filed:24/02/1999
Date Published:23/01/2001
Assignee:HemaSure Inc., Marlborough, MA, USA


 
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