Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US6190910

Title:Mouse embryonic stem cell lines
Inventors:KUSA
kabe, Moriaki; Ibaragi, Japan
Kamon, Toshio; Tokyo, Japan
Summary:Described herein are embryonic stem cells derived from inbred mouse strains. The invention relates to embryonic stem cell lines C-6, C-2, Cr/A-3, DB1, and B6-26 which have been derived from the inbred mice strains C3H/HeN, BALB/c, DBA/1J, and C57BL/6N, respectively, such that the embryonic stem cells are alkaline phosphatase positive and express a C3H specific antigen. Applications are provided for the production of knockout mice in genetic research, for the analysis of cell genealogical trees and for the establishment of embryonic stem cell lines.
Abstract:Embryonic stem cell lines C-6 and C-2, Cr/A-3, DB1, and B6-26 have been derived from the inbred mice strains C3H/HeN, BALB/c, DBA/1J, and C57BL/6N, respectively. The embryonic stem cells are alkaline phosphatase positive and express a C3H specific antigen. The embryonic stem cell lines are useful in genetic research and the production of knockout mice.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6190910
Application Number:US1999000439284
Date Filed:15/11/1999
Date Published:20/02/2001
Assignee:The Institute of Physical and Chemical Research, Saitama, Japan


 
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