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Stem Cell Related Patent Number US6207454
| Title: | Method for enhancing the effciency of gene transfer with stem cell factor (SCF) polypeptide | | Inventors: | Zsebo, Krisztina M.; Thousand Oaks, CA, USA
Bosselman, Robert A.; Thousand Oaks, CA, USA
Suggs, Sidney V.; Newbury Park, CA, USA
Martin, Francis H.; Thousand Oaks, CA, USA | | Summary: | Described herein are methods of enhancing the efficiency of transfer of a polynucleotide into a target mammalian cell in vitro, via a process of exposing the cell that expresses a stem cell factor receptor to a stem cell factor, and introducing a polynucleotide into the cell in vitro. Therapeutic applications in the treatment of blood disorders are included. This invention represents a continuation of other applications filed by the same assignee and inventors. | | Abstract: | Novel stem cell factors, oligonucleotides encoding the same, and methods of production, are disclosed. Pharmaceutical compositions and methods of treating disorders involving blood cells are also disclosed. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US6207454 | | Application Number: | US1998000224681 | | Date Filed: | 31/12/1998 | | Date Published: | 27/03/2001 | | Assignee: | Amgen Inc., Thousand Oaks, CA, USA |
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