Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US6225459

Title:TEC promoter
Inventors:Mano, Hiroyuki; Tochigi, Japan
Sakata, Tsuneaki; Osaka, Japan
Hasegawa, Mamoru; Ibaraki, Japan
Summary:Described herein are DNA with Tec tyrosine kinase promoter activity, methods and uses thereof. The invention relates to a recombinant DNA with promoter activity of Tec tyrosine kinase and a vector having incorporated within it the promoter to thereby enable a high level expression of an exogenous gene in hematopoietic stem cells and hepatic cells. Specific nucleotide sequences are provided, as are therapeutic applications in the expression of foreign genes in hematopoietic stem cells and liver cells.
Abstract:The present invention provides a DNA having promoter activity of Tec tyrosine kinase and a vector having incorporated within it the promoter to thereby enable a high level expression of an exogenous gene in hematopoietic stem cells and hepatic cells.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6225459
Application Number:US1999000142529
Date Filed:12/08/1999
Date Published:01/05/2001
Assignee:Dnavec Research Inc., Tsukuba, Japan


 
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