Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US6241984

Title:Human hematopoietic progenitor cell preparations and their expansion in a liquid medium
Inventors:Hoffman, Ronald; Palo Alto, CA, USA
Brandt, John; Palo Alto, CA, USA
Summary:This invention describes methods and materials for transplanting autologous hematopoietic cells in a patient receiving cytoreductive therapy, via the expansion of cells in a medium containing the GM-CSF/IL-3 fusion protein and a mast cell growth factor. The culture medium is described as being preferably free of stromal cells while containing at least one cytokine effective for supporting the cells. Methods of removal, expansion and administration of the cells are provided, as are therapeutic applications in reducing metastases.
Abstract:A process for supporting hematopoietic progenitor cells in a culture medium which contains at least one cytokine effective for supporting the cells and preferably, is essentially free of stromal cells.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6241984
Application Number:US1994000226513
Date Filed:31/03/1994
Date Published:05/06/2001
Assignee:The Indiana University Foundation, Bloomington, IN, USA


 
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