Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US6251669

Title:Neuronal progenitor cells and uses thereof
Inventors:Luskin, Marla B.; Decatur, GA, USA
Summary:This invention introduces compositions enriched in non-tumor neuronal progenitor cells with neuron-specific markers which are capable of differentiating into neuronal cells. Described herein is an isolated cellular composition comprising greater than approximately 90% mammalian, non tumor-derived, neuronal progenitor cells which express a neuron-specific marker and which can give rise to progeny that differentiate into neuronal cells. Therapeutic applications include transplantation in the treatment of neuronal disorders such as Alzheimer's, Parkinson's and Huntington's diseases.
Abstract:The present invention provides an isolated cellular composition comprising greater than about 90% mammalian, non tumor-derived, neuronal progenitor cells which express a neuron-specific marker and which can give rise to progeny which can differentiate into neuronal cells. Also provided are methods of treating neuronal disorders utilizing this cellular composition.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6251669
Application Number:US1998000003006
Date Filed:05/01/1998
Date Published:26/06/2001
Assignee:Emory University, Atlanta, GA, USA


 
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