Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US6251671

Title:Compositions and methods of making embryonic stem cells
Inventors:Hogan, Brigid L. M.; Brentwood, TN, USA
Zhao, Guang-Quan; Nashville, TN, USA
Summary:This invention introduces methods and materials for inducing the proliferation and differentiation of spermatogonial cells, and extending the survival of the spermatocytes in culture via treatment with bone morphogenic protein 8. Therapeutic applications include cellular proliferation and differentiation in the treatment of male infertility.
Abstract:The invention relates to cell proliferation, cell differentiation, male infertility, male fertility and to compositions and methods involved therein. Also methods of culturing spermatogonial stem cells with bone morphogenetic protein 8 are disclosed.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6251671
Application Number:US1997000808346
Date Filed:28/02/1997
Date Published:26/06/2001
Assignee:Vanderbilt University, Nashville, TN, USA


 
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