Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US6258939

Title:PSCA antibodies and hybridomas producing them
Inventors:Reiter, Robert E.; Los Angeles, CA, USA
Summary:Described herein is the prostate stem cell antigen protein, designated PSCA, and methods of its use specifically in the diagnosis and treatment of prostate cancer, in the production of vaccines and in the generation of antibodies for use in assays. The invention relates to a hybridoma and the monoclonal antibodies that it produces. Specific amino acid sequences and binding properties are disclosed. This invention represents a continuation of other applications filed by the same assignee and inventors.
Abstract:The invention provides a novel prostate cell-surface antigen, designated Prostate Stem Cell Antigen (PSCA), which is widely over-expressed across all stages of prostate cancer, including high grade prostatic intraepithelial neoplasia (PIN), androgen-dependent and androgen-independent prostate tumors.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6258939
Application Number:US1998000203939
Date Filed:02/12/1998
Date Published:10/07/2001
Assignee:The Regents of the University of California, Oakland, CA, USA


 
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