Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US6261791

Title:Method for diagnosing cancer using specific PSCA antibodies
Inventors:Reiter, Robert E.; Los Angeles, CA, USA
Witte, Owen N.; Sherman Oaks, CA, USA
Summary:Described herein is the novel prostate stem cell antigen protein, PSCA, and methods of its use in the diagnosis and treatment of prostate cancer, the production of vaccines or the generation of antibodies for use in assays. The invention relates to a novel prostate cell-surface antigen, designated PSCA, which is widely over-expressed across all stages of prostate cancer, bladder cancer and bone metastasis of prostate cancer. Claims of the invention include methods by which antibodies specific to PSCA are used in the diagnosis and treatment of these cancers. This invention represents a continuation of other applications filed by the same assignee and inventors.
Abstract:The invention provides a novel prostate cell-surface antigen, designated Prostate Stem Cell Antigen (PSCA), which is widely over-expressed across all stages of prostate cancer, bladder cancer and bone metastasis of prostate cancer. Antibodies specific to PSCA are used for diagnosis of these cancers.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6261791
Application Number:US1999000318503
Date Filed:25/05/1999
Date Published:17/07/2001
Assignee:The Regents of the University of California, Oakland, CA, USA


 
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