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Stem Cell Related Patent Number US6261841
| Title: | Compositions, kits, and methods for modulating survival and differentiation of multi-potential hematopoietic progenitor cells | | Inventors: | Cohen, Isaac; Wilmette, IL, USA
Lefebvre, Phil; Chicago, IL, USA
Lin, Jiandie; Evanston, IL, USA
Linzer, Daniel; Evanston, IL, USA | | Summary: | Described herein are methods and materials for maintaining mammalian hematopoietic progenitor cells in vitro, and modulating the survival and differentiation of mammalian hematopoietic progenitor cells via a process of maintaining the cells in a nutritive medium containing a placental glycoprotein hormone of the murine prolactin family, namely, either murine prolactin-like protein E or F. The invention relates to methods, compositions, and kits which can be used for the in vitro or ex vivo expansion of hematopoietic precursor cells or for the treatment of a disorder associated with aberrant hematopoiesis, such as pre-eclampsia and thrombocytopenia. | | Abstract: | | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US6261841 | | Application Number: | US2000000602848 | | Date Filed: | 23/06/2000 | | Date Published: | 17/07/2001 | | Assignee: | The Board of Trustees of Northwestern University, Evanston, IL, USA |
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