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Stem Cell Related Patent Number US6280957
| Title: | Costimulatory blockade and mixed chimerism in allo-transplantation | | Inventors: | Sayegh, Mohamed; Westwood, MA, USA
Sykes, Megan; Charlestown, MA, USA | | Summary: | Described herein are methods and materials for promoting the acceptance of an allograft in a recipient. The invention relates to the use of a blockade of costimulation and hematopoietic stem cells in an allograft transplantation for a recipient mammal receiving a graft from a donor mammal of the same species. Specific properties of the inhibitor of the CD40 ligand-CD40 costimulatory interaction are provided. | | Abstract: | Use of the blockade of costimulation and hematopoietic stem cells in allograft transplantation. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US6280957 | | Application Number: | US1999000245614 | | Date Filed: | 04/02/1999 | | Date Published: | 28/08/2001 | | Assignee: | The General Hospital Corporation, Charlestown, MA, USA |
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