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Stem Cell Related Patent Number US6335195
| Title: | Method for promoting hematopoietic and mesenchymal cell proliferation and differentiation | | Inventors: | Rodgers, Kathleen E.; Long Beach, CA, USA
DiZerega, Gere S.; Pasadena, CA, USA | | Summary: | This invention describes methods of promoting hematopoietic and mesenchymal cell proliferation and differentiation via contacting the cells with angiotensinogen, angiotensin I or II, and analogues or fragments thereof. The invention relates to improved methods and materials, including a cell culture medium and kits, for the promotion of hematopoietic and mesenchymal stem and lineage-specific cell proliferation and differentiation. | | Abstract: | The present invention provides methods, improved cell culture medium and kits for promoting hematopoietic and mesenchymal stem and lineage-specific cell proliferation and differentiation by growth in the presence of angiotensinogen, angiotensin I (AI); AI analogues, AI fragments and analogues thereof, angiotensin II (AII), AII analogues, AII fragments or analogues thereof or AII AT.sub.2 type 2 receptor agonists, either alone or in combination with other growth factors and cytokines. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US6335195 | | Application Number: | US1998000012400 | | Date Filed: | 23/01/1998 | | Date Published: | 01/01/2002 | | Assignee: | Maret Corporation, Newport Beach, CA, USA |
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