Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US6335195

Title:Method for promoting hematopoietic and mesenchymal cell proliferation and differentiation
Inventors:Rodgers, Kathleen E.; Long Beach, CA, USA
DiZerega, Gere S.; Pasadena, CA, USA
Summary:This invention describes methods of promoting hematopoietic and mesenchymal cell proliferation and differentiation via contacting the cells with angiotensinogen, angiotensin I or II, and analogues or fragments thereof. The invention relates to improved methods and materials, including a cell culture medium and kits, for the promotion of hematopoietic and mesenchymal stem and lineage-specific cell proliferation and differentiation.
Abstract:The present invention provides methods, improved cell culture medium and kits for promoting hematopoietic and mesenchymal stem and lineage-specific cell proliferation and differentiation by growth in the presence of angiotensinogen, angiotensin I (AI); AI analogues, AI fragments and analogues thereof, angiotensin II (AII), AII analogues, AII fragments or analogues thereof or AII AT.sub.2 type 2 receptor agonists, either alone or in combination with other growth factors and cytokines.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6335195
Application Number:US1998000012400
Date Filed:23/01/1998
Date Published:01/01/2002
Assignee:Maret Corporation, Newport Beach, CA, USA


 
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