Methods comprising apoptosis inhibitors for the generation of transgenic pigs

Stem Cell Clinic
Patient Application
FAQ
Contact
Locations
News
Videos
Research
Patents
3D Culture/Scaffold
Administration
Differentiation
Expansion
Extraction/Preservation
Mobilization
Type
USE
 


Stem Cell Related Patent Number US6342220

Title:Agonist antibodies
Inventors:Adams, Camellia W.; Mountain View, CA, USA
Carter, Paul J.; San Francisco, CA, USA
Fendly, Brian M.; Half Moon Bay, CA, USA
Gurney, Austin L.; Belmont, CA, USA
Summary:This invention introduces novel thrombopoietin receptor agonist antibodies, methods and uses thereof. Central to the invention are various forms of c-mpl agonist antibodies which have been shown to influence the replication, differentiation and maturation of blood cells, especially megakaryocytes and megakaryocyte progenitor cells. Amino acid sequences are disclosed, as are uses of these compounds in the treatment of thrombocytopenia. Therapeutic applications include the treatment of immunological or hematological disorders
Abstract:Various forms of c-mpl agonist antibodies are shown to influence the replication, differentiation or maturation of blood cells, especially megakaryocytes and megakaryocyte progenitor cells. Accordingly, these compounds may be used for treatment of thrombocytopenia.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6342220
Application Number:US1997000918148
Date Filed:25/08/1997
Date Published:29/01/2002
Assignee:Genentech, Inc., South San Francisco, CA, USA


 
Copyright © 2007 The Institute for Cellular Medicine  6/13/2021