Methods comprising apoptosis inhibitors for the generation of transgenic pigs

Stem Cell Clinic
Patient Application
FAQ
Contact
Locations
News
Videos
Research
Patents
3D Culture/Scaffold
Administration
Differentiation
Expansion
Extraction/Preservation
Mobilization
Type
USE
 


Stem Cell Related Patent Number US6348050

Title:Infusion systems for creating microenvironments in a living body
Inventors:Hartlaub, Jerome T.; New Brighton, MN, USA
Summary:Described herein are methods of maintaining a microenvironment in a living body via implantable infusion systems which deliver therapy to target sites. The invention relates to implantable infusion systems for the prolonged infusion of a carefully designed medicament composition which delivers exogenous substances to maintain a microenvironment in the living body. Further disclosed are components of the medicament compositions which include stem cells including homographs and allographs, adhesive peptides, substances which inhibit fibroblast growth, genetically modified cells which produce the exogenous substances, and nerve growth factor (NGF). Also provided are the means with which the replication of cells in a reservoir may be used to keep cells alive in a dormant state until infusion.
Abstract:The invention provides implantable infusion systems, including apparatus and methods, for prolonged infusion of a carefully designed medicament composition to create and maintain a comprehensive microenvironment at a target area in a living body. The composition may include living cells to treat a particular disease and which deliver exogenous substances to maintain a microenvironment in the living body. The invention contemplates medicament compositions that include stem cells (neuro or otherwise), including homographs and allographs, adhesive peptides, substances which inhibit fiberblast growth, genetically modified cells which produce useful exogenous substances, nerve growth factor (NGF), previously harvested cells from a living body. In another aspect, the invention contemplates the replication of cells in a reservoir, for example, to keep cells alive in a dormant state until infusion.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6348050
Application Number:US1999000303033
Date Filed:30/04/1999
Date Published:19/02/2002
Assignee:Medtronic, Inc., Minneapolis, MN, USA


 
Copyright © 2007 The Institute for Cellular Medicine  6/22/2021