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Stem Cell Related Patent Number US6348444
| Title: | Human growth hormone to stimulate hematopoiesis and immune reconstitution after hematopoietic stem cell transplantation in humans | | Inventors: | Chappel, Scott C.; Milton, MA, USA | | Summary: | Described herein are novel uses of human growth hormone for the stimulation of hematopoiesis and immune reconstitution. The invention relates to the use of human growth hormone for the manufacture of a medicament for stimulating hematopoiesis and immune reconstitution when administered to a patient approximately 30 days after transplantation of hematopoietic stem cells. Further disclosed are methods for producing a pharmaceutical composition comprised of a pharmaceutically acceptable carrier, excipient, stabilizer or auxiliary agent, and an effective amount of the human growth hormone of SEQ ID NO:1 or a fragment, analog, variant or chemical derivative thereof. Therapeutic applications include the prevention of graft rejection. | | Abstract: | The invention relates to the use of human growth hormone for the manufacture of a medicament for stimulating hematopoiesis and immune reconstitution to be administered to a patient in need thereof about 30 days post-transplantation of hematopoietic stem cells. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US6348444 | | Application Number: | US1999000465461 | | Date Filed: | 17/12/1999 | | Date Published: | 19/02/2002 | | Assignee: | Applied Research Systems ARS Holding N.V., Curacao, Netherlands |
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