Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US6498034

Title:Method of producing dendritic cells
Inventors:Strobl, Herbert; Vienna, Austria
Summary:This invention introduces a method for producing dendritic cells via culturing of a cell sample composed of human CD34-positive progenitor cells under conditions free of plasma and serum while in the presence of a combination of cytokines including transdermal growth factor-beta1. The invention relates to a process for preparing CD1a-positive and Lag reactive dendritic cells from human hematopoietic progenitor cells in the presence of a combination of cytokines to produce dendritic cells, where the combination of cytokines include TGF-?1. Methods and materials are disclosed.
Abstract:The present invention relates to a method for producing dendritic cells from human hematopoietic progenitor cells by obtaining a cell sample that includes human progenitor cells and culturing the cell sample under plasma-free and serum-free conditions in the presence of a combination of cytokines to produce dendritic cells, where the combination of cytokines include TGF-.beta.1.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6498034
Application Number:US1999000277668
Date Filed:26/03/1999
Date Published:24/12/2002
Assignee:Novartis AG, Basel, Switzerland


 
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