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Stem Cell Related Patent Number US6498034
| Title: | Method of producing dendritic cells | | Inventors: | Strobl, Herbert; Vienna, Austria | | Summary: | This invention introduces a method for producing dendritic cells via culturing of a cell sample composed of human CD34-positive progenitor cells under conditions free of plasma and serum while in the presence of a combination of cytokines including transdermal growth factor-beta1. The invention relates to a process for preparing CD1a-positive and Lag reactive dendritic cells from human hematopoietic progenitor cells in the presence of a combination of cytokines to produce dendritic cells, where the combination of cytokines include TGF-?1. Methods and materials are disclosed. | | Abstract: | The present invention relates to a method for producing dendritic cells from human hematopoietic progenitor cells by obtaining a cell sample that includes human progenitor cells and culturing the cell sample under plasma-free and serum-free conditions in the presence of a combination of cytokines to produce dendritic cells, where the combination of cytokines include TGF-.beta.1. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US6498034 | | Application Number: | US1999000277668 | | Date Filed: | 26/03/1999 | | Date Published: | 24/12/2002 | | Assignee: | Novartis AG, Basel, Switzerland |
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