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Stem Cell Related Patent Number US6514513
| Title: | Costimulatory blockade and mixed chimerism in transplantation | | Inventors: | Sykes, Megan; Charlestown, MA, USA | | Summary: | Described herein are methods of promoting the acceptance of a xenograft within a recipient. The invention relates to a method of promoting acceptance, by a recipient mammal, of a graft from a donor mammal of a second species. Further disclosed are processes by which a recipient is administered an inhibitor of a costimulatory pathway. Also provided are methods of introducing into the recipient mammal hematopoietic stem cells, as well as methods of implantation of the graft in the recipient. | | Abstract: | Use of blockade of costimulation and hematopoietic stem cell transplantation in the promotion of graft acceptance. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US6514513 | | Application Number: | US1999000244447 | | Date Filed: | 04/02/1999 | | Date Published: | 04/02/2003 | | Assignee: | The General Hospital Corporation, Boston, MA, USA |
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