Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US6531505

Title:Immunosuppressive agents
Inventors:Xu, Qiang; Nanjing City, Jiangsu Province, 210009, P.R., China
Summary:Described herein are flavanoid and chromone derivatives extracted from Rhizoma Smilacis Glabrae and used as immunosuppressive agents. The invention relates to methods of treatment of diseases due to an abnormal immune response induced by activated T cells via the administration of an effective amount of an immunosuppressive agent having a selective inhibitory activity against activated T cells. Therapeutic applications of such immunosuppressive agents include the treatment of autoimmune disease, inflammatory reaction, fibrosis or dysfunction caused by autoimmune disease, and in the treatment of transplant rejection or graft-versus-host disease.
Abstract:An immunosuppressive agent which is very effective for treating autoimmune disease, inflammatory reaction, fibrosis or dysfunction caused by autoimmune disease and related disease thereof with tissue injury or infection, rejection of transplantation, graft versus host disease by bone marrow (hematopoietic stem cell) transplantation, or allergic disease, by selectively inhibiting the activated T cells, is provided.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6531505
Application Number:US1999000393704
Date Filed:10/09/1999
Date Published:11/03/2003
Assignee:Xu; Qiang, Nanjing, China


 
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