Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US6555318

Title:Method for identification of cell growth or differentiation factors
Inventors:Keller, Gordon M.; Denver, CO, USA
Hawley, Robert G.; Toronto, Canada
Choi, Kyunghee; Baltimore, MD, USA
Summary:Described herein are immortalized precursor cell populations derived from embryonic stem cell populations, methods and uses thereof. The invention relates to a method of identifying at least one nucleic acid sequence that is associated with differentiation from embryonic stem cells, in which novel immortalized precursor cell populations are derived from embryonic stem cells. Further disclosed is an assay to identify regulatory compounds capable of controlling cell growth for therapeutic and experimental use. Applications are included, such as in the treatment of genetic diseases in hematopoietic lineage cells such as in sickle cell anaemia or b-thalassemia.
Abstract:The present invention relates to novel immortalized precursor cell populations derived from embryonic stem cell populations and methods to produce such cell populations. Also disclosed is an assay to identify regulatory compounds capable of controlling cell growth for therapeutic and experimental use.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6555318
Application Number:US2001000767893
Date Filed:22/01/2001
Date Published:29/04/2003
Assignee:National Jewish Medical and Research Center, Denver, CO, USA


 
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