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Stem Cell Related Patent Number US6610654
| Title: | Inhibitor of stem cell proliferation and uses thereof | | Inventors: | Tsyrlova, Irena; Gaithersburg, MD, USA | | Summary: | This invention describes inhibitors of stem cell proliferation, methods and uses thereof. The invention relates to methods and materials for the isolation and use of stem cell inhibiting factors, composed of hemoglobin chains, for the regulation of abnormal stem cell cycles and for the acceleration of post-chemotherapy peripheral blood cell recovery. Associated amino acid sequences are disclosed. Therapeutic applications are included, such as in the protection of stem cells from antiviral agents, in the treatment of cancer, and in the maintenance of mammalian hematopoietic stem cells ex vivo. | | Abstract: | Disclosed and claimed are methods for the isolation and use of stem cell inhibiting factors for regulating the abnormal stem cell cycle and for accelerating the post-chemotherapy peripheral blood cell recovery. Also disclosed and claimed are the inhibitors of stem cell proliferation. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US6610654 | | Application Number: | US2002000128581 | | Date Filed: | 24/04/2002 | | Date Published: | 26/08/2003 | | Assignee: | Wellstat Therapeutics Corporation, Gaithersburg, MD, USA |
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