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Stem Cell Related Patent Number US6627191
| Title: | Anti-transforming growth factor Beta (TGF-.beta.) treated stem cell composition and method | | Inventors: | Bartelmez, Stephen H.; Seattle, WA, USA
Sitnicka, Ewa; Lund, Sweden
Ruscetti, Frank; New Market, MD, USA | | Summary: | This invention describes a novel transforming growth factor-? antibody treated stem cell composition, and rapid in vivo hematopoietic system repopulation. The invention relates to stem cell compositions comprising anti-TGF-? treated stem cells which are viable for at least 14 days in vitro or ex vivo without replication or differentiation. Further disclosed are methods for rapid and long term in vitro hematopoiesis and in vivo hematopoietic reconstitution using such anti-TGF-? treated stem cells. Methods, materials and uses are provided. | | Abstract: | The invention relates to stem cell compositions comprising anti-TGF-.beta. treated stem cells which are viable for at least 14 days in culture without replication or differentiation and methods for rapid and long term in vitro hematopoiesis and in vivo hematopoietic reconstitution using such anti-TGF-.beta. treated stem cells. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US6627191 | | Application Number: | US2000000490520 | | Date Filed: | 25/01/2000 | | Date Published: | 30/09/2003 | | Assignee: | Seattle Biomedical Research Institute, Seattle, WA, USA |
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