Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US6635802

Title:Nuclear transfer using cells cultured in serum starvation media containing apoptosis inhibitors
Inventors:Piedrahita, Jorge A.; College Station, TX, USA
Lee, Chang-Kyu; Suwon, Republic of Korea
Weaks, Regina; Richardson, TX, USA
Bazer, Fuller; College Station, TX, USA
Summary:This invention provides methods and compositions for increasing the efficiency of nuclear transfer using apoptosis inhibitors, and for the production of transgenic and non-transgenic mammals from cultured cells or cell lines. Methods for cloning mammals, and for producing transgenic and chimeric mammalian tissues and mammals, and chimeric cell lines are also disclosed.
Abstract:Provided are methods and compositions for increasing the efficiency of nuclear transfer using apoptosis inhibitors, and for the production of transgenic and non-transgenic mammals from cultured cells or cell lines. Methods for cloning mammals, and for producing transgenic and chimeric mammalian tissues and mammals, and chimeric cell lines are also provided.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6635802
Application Number:US2001000758024
Date Filed:10/01/2001
Date Published:21/10/2003
Assignee:The Texas AandM University System, College Station, TX, USA


 
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