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Stem Cell Related Patent Number US6653526
| Title: | Transgenic mice exhibiting increased susceptibility to seizures | | Inventors: | Leviten, Michael W.; Palo Alto, CA, USA | | Summary: | This invention describes an isolated mouse cell whose genome comprises a disruption in a nucleic acid sequence. The resulting transgenic mouse exhibits mutations in a ubiquitin-specific protease 16 gene, which are useful mutations in the modeling of certain diseases and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions. | | Abstract: | The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a ubiquitin-specific protease 16 gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US6653526 | | Application Number: | US2001000904198 | | Date Filed: | 11/07/2001 | | Date Published: | 25/11/2003 | | Assignee: | Deltagen, Inc., Redwood, CA, USA |
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