Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US6670151

Title:Porcine stem cell factor varients and recombinant cells expressing such polypeptides
Inventors:Baetscher, Manfred; Portland, OR, USA
Summary:Described herein are novel porcine stem cell factor variants, methods and uses thereof. The invention relates to newly identified polynucleotides and polypeptides encoded by such polynucleotides which constitute membrane-bound porcine stem cell factors that are involved in the culture of pluripotent or totipotent porcine cells. Specific amino acid sequences are disclosed, as are applications in the generation of stem cells to support porcine bone marrow cell proliferation.
Abstract:This invention relates to newly identified polynucleotides, polypeptides encoded by such polynucleotides, the use of such polynucleotides and polypeptides, as well as the production and isolation of such polynucleotides and polypeptides. More particularly, the polynucleotides and polypeptides of the present invention have been identified as porcine stem cell factors, and in particular membrane-bound porcine stem cell factors, and still more particularly as being involved in the culture of pluripotent or totipotent porcine cells.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6670151
Application Number:US2000000485639
Date Filed:25/04/2000
Date Published:30/12/2003
Assignee:BioTransplant, Inc., Medford, MA, USA


 
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