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Stem Cell Related Patent Number US6703209
| Title: | Porcine totipotent cells and method for long-term culture | | Inventors: | Baetscher, Manfred; Portland, OR, USA
Brem, Gottfried; Hilgetshausen-Tandem, Germany | | Summary: | This invention describes the culturing of a porcine pluripotent cell factor (PSCF) in the presence of STO8 feeder cells expressing a PSCF. The PSCF is also termed herein “porcine steel factor, which is described preferably as being a membrane-bound PSCF on transfected murine STO feeder cells. Applications are provided in the establishment of pluripotent or totipotent porcine cell lines, especially for the culture of porcine primordial germ cells (PGCs). | | Abstract: | This invention provides a method of using a porcine stem cell factor (PSCF), which may also be termed porcine steel factor, which is preferably membrane-bound PSCF on transfected murine STO feeder cells, for establishing pluripotent or totipotent porcine cell lines, especially for the culture of porcine primordial germ cells (PGCs). | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US6703209 | | Application Number: | US1998000133352 | | Date Filed: | 13/08/1998 | | Date Published: | 09/03/2004 | | Assignee: | BioTransplant, Inc., Charlestown, MA, USA |
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